Mandel Emmanuil Semenovich (1851, Rezhitsa (now - Rezekne) – 1916, Petrograd) – lawyer, entrepreneur, and public figure.

Emmanuil Mandel graduated from the Law Faculty of Kharkov University, settled in St. Petersburg, and practiced law, serving as an attorney and solicitor. In the late 19th and early 20th centuries, he was chairman of the board of the Olekminsky Gold Mining Joint-Stock Company and the Amur Shipping and Trade Society, a member of the boards of the Baltic Cotton Spinning and Weaving Manufactory Joint-Stock Company and the Russian Insurance Society. He was deputy chairman of the Society for the Aid of Poor Jews, and from 1911, its chairman, and a member of the board of the Jewish community of St. Petersburg. During the First World War, he was the chairman of the Committee for Assistance to the Families of Jewish Soldiers and participated in organizing assistance to Jewish victims of military action who were evicted from front-line areas.